Christopher Evans Publications
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Weber, E., Evans, C.J. & Barchas, J.D. Opioid peptide dynorphin: predominance of the aminoterminal octapeptide fragment in rat brain regions. Nature, 299: 77-79, 1982.

Evans, C.J., Erdelyi, E., Weber, E. & Barchas, J.D. Identification of pro-opiomelanocortin derived peptides in the human adrenal medulla. Science, 221: 957-960, 1983.

Weber, E., Esch, F.S., Bohlen, P., Paterson, S., Corbett, A.D., McKnight, A.T., Kosterlitz, H.W., Barchas, J.D. & Evans, C.J. Metorphamide: Isolations, structure and biologic activity of a novel amidated opioid octapeptide from bovine brain. Proc. Natl. Acad. Sci., 80: 7362-7366, 1983.

Evans, C.J., Barchas, J.D., Esch, F.S., Bohlen, P. & Weber, E. Isolation and characterization of an endogenous C-terminal fragment of the alpha-neo-endorphin/dynorphin precursor from bovine caudate nucleus. J. Neurosci., 5(7): 1803-1807, 1985.

Seizinger, B.R., Liebisch, D.C., Gramsch, C., Herz, A., Weber, E., Evans, C.J., Esch, F.S. & Bohlen, P. Isolation and structure of a novel C-terminally amidated opioid peptide, amidorphin, from bovine adrenal medulla. Nature, 313: 57-62, 1985.

Maidment, N.T., Brumbaugh, D.R., Rudolph, V.D., Erdelyi, E., Barchas, J.D. & Evans, C.J. Microdialysis of extracellular endogenous opioid peptides from rat brain in vivo. Neuroscience, 33: 549-557, 1989

Evans, C.J., Keith, D.E., Jr., Morrison, H., Magendzo, K., & Edwards, R.H. Cloning of a delta opioid receptor by functional expression. Science, 258: 1952-1955, 1992.

von Zastrow, M., Keith, D.E., Jr., & Evans, C.J. Agonist-induced state of the delta-opioid receptor that discriminates between opioid peptides and opiate alkaloids. Molecular Pharmacology, 44: 166-172, 1993.

Kaufman, D.L., Keith, D.E., Jr., Anton, B., Tian, J., Magendzo, K., Newman, D., Tran, T.H., Lee, D.S., Wen, C., Xia, Y-R, Lusis, A.J., & Evans, C.J. Characterization of the murine mu opioid receptor gene. J. Biol. Chem., 270(26): 15877-15883, 1995.

Befort, K., Tabbara, L., Bausch, S., Chavkin, C., Evans, C., & Kieffer, B. The conserved aspartate residue in the third putative transmembrane domain of the delta-opioid receptor is not the anionic counterpart for cationic opiate binding but is a constituent of the receptor bindng site. Mol. Pharm., 49: 216-223, 1996.

Sternini, C., Spann, M., Anton, B., Keith, D.E., Bunnett, N.W., von Zastrow, M., Evans, C., & Brecha, N.C. Agonist selective endocytosis of mu opioid receptor by neurons in vivo. Proc. Natl. Acad. Sci., 93: 9241-9246, 1996.

Keith, D.E., Murray, S.R., Zaki, P.A., Chu, P.C., Lissin, D.V., Kang, L., Evans, C.J. & von Zastrow, M. Morphine activates opioid receptors without causing their rapid internalization. J. Biol. Chem., 271: 19021-19024, 1996.

Li, X., Keith, Jr., D.E., & Evans, C.J. Mu opioid receptor-like sequences are present throughout vertebrate evolution. Journal of Molecular Evolution, 43: 179-184, 1996.

Piros, E.T., Prather, P.L., Law, P.Y., Evans, C.J., & Hales T.G. Voltage-dependent inhibition of L-types Ca²⁺ channels by cloned ?- and ?-opioid receptors. Molecular Pharmacology, 50: 947-956, 1996.

Li, X., Keith, D.E., Jr., & Evans, C.J. Multiple opioid receptor-like genes are identified in diverse vertebrate phyla. FEBS Lets, 397: 25-29, 1996.

Yu, T-P., Fein, J., Evans, C.J., & Xie, C.W. Orphanin FQ inhibits synaptic transmission and long-term potentiation in rat hippocampus. Hippocampus, 7: 88-94, 1997.

Olive, M.F., Anton, B., Micevych, P., Evans, C.J., & Maidment, N.T. Presynaptic and postsynaptic localization of mu and delta opioid receptors in dorsal and ventral striatopallidal pathways. J. Neuroscience, 17: 7471-7479, 1997.

Keith, D.E., Anton, B., Murray, S.R., Zaki, P.A., Chu, P.C., Lissin, D.V., Monteillet-Agius, G., Stewart, P.L., Evans, C.J., & von Zastrow, M. Mu opioid receptor internalization: Opiate drugs have differential effects on a conserved endocytic mechanism in vitro and in the mammalian brain. Mol. Pharm.,53: 377-384, 1998.

Zaki, P.A., Keith, D.E. Jr., Brine, G.A., Carroll, F.I, & Evans, C.J. The role of G protein activation in agonist-dependent mu-opioid receptor internalization, in press JPET, 292 1127-1134 2000.